STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q4E602_TRYCC6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase, putative. (1021 aa)    
Predicted Functional Partners:
pfk
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
   
 0.685
Q4CXF2_TRYCC
Uncharacterized protein.
    
 0.632
Q4DNI3_TRYCC
Uncharacterized protein.
    
 0.632
Q4E2M9_TRYCC
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.629
Q4E5N1_TRYCC
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.629
Q4D7D8_TRYCC
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
    
 0.621
Q4DDP0_TRYCC
Phosphoglycerate mutase protein, putative.
   
 0.621
Q4DL01_TRYCC
Phosphoglycerate mutase protein, putative.
   
 0.621
Q4DSP9_TRYCC
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
    
 0.621
Q4DV43_TRYCC
Triosephosphate isomerase.
  
 
 0.606
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener
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