STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORA83424.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1179 aa)    
Predicted Functional Partners:
ORA78858.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.994
ORA79945.1
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.993
ORA81536.1
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.991
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 0.991
ORA78996.1
Hypothetical protein; Contains 3'-5'exonuclease domain; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.986
ORA77342.1
3'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.966
ORA76761.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.963
ORA77012.1
Single-stranded DNA-binding protein; Binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.937
ORA79881.1
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.925
recA
Intein-containing recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
   
 0.833
Your Current Organism:
Mycolicibacter kumamotonensis
NCBI taxonomy Id: 354243
Other names: CCUG 51961, DSM 45093, GTC 2729, JCM 13453, M. kumamotonensis, Mycobacterium kumamotoense, Mycobacterium kumamotonense, Mycobacterium kumamotonense Masaki et al. 2007, Mycolicibacter kumamotonensis (Masaki et al. 2007) Gupta et al. 2018, strain CST 7247
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