STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshBN-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. (308 aa)    
Predicted Functional Partners:
mshC
cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
 
 
 0.988
mshA
D-inositol-3-phosphate glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
 
 0.947
mshD
Mycothiol synthase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
   
 0.926
ORA79894.1
Disulfide bond formation protein DsbA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.741
ORA82199.1
Disulfide bond formation protein DsbA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.736
ORA81278.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.733
ORA83111.1
Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.668
ORA82266.1
Phosphatidylinositol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.667
ORA81280.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.655
ORA82265.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.646
Your Current Organism:
Mycolicibacter kumamotonensis
NCBI taxonomy Id: 354243
Other names: CCUG 51961, DSM 45093, GTC 2729, JCM 13453, M. kumamotonensis, Mycobacterium kumamotoense, Mycobacterium kumamotonense, Mycobacterium kumamotonense Masaki et al. 2007, Mycolicibacter kumamotonensis (Masaki et al. 2007) Gupta et al. 2018, strain CST 7247
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.