STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEP25235.1Acetolactate synthase, small subunit. (210 aa)    
Predicted Functional Partners:
SEO61119.1
Acetolactate synthase, large subunit.
 
 0.999
SEP03319.1
Acetolactate synthase, large subunit.
 
 0.999
SEP25198.1
Acetolactate synthase, large subunit.
 
 0.999
SEP25252.1
Ketol-acid reductoisomerase.
 
 
 0.999
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
 
 
 0.995
SEP25131.1
2-isopropylmalate synthase.
 
 
 0.985
leuB-2
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.984
SEP25420.1
Aspartate kinase.
 
 
 0.976
SEO81535.1
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.973
SEO81569.1
D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.973
Your Current Organism:
Niastella yeongjuensis
NCBI taxonomy Id: 354355
Other names: DSM 17621, KACC 11466, N. yeongjuensis, Niastella yeongjuensis Weon et al. 2006, strain GR20-13
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.