STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa)    
Predicted Functional Partners:
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 0.999
panD
L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.985
SIR43515.1
Branched-chain amino acid aminotransferase.
    
 0.911
ilvD
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
     
 0.911
SIS12106.1
Branched-chain amino acid aminotransferase.
    
 0.911
SIQ66235.1
Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains.
 
  
 0.827
SIR69850.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.819
SIQ10983.1
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.776
rsmI
16S rRNA (cytidine1402-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
      0.639
SIR82801.1
Ribosomal large subunit pseudouridine synthase D.
       0.639
Your Current Organism:
Mucilaginibacter lappiensis
NCBI taxonomy Id: 354630
Other names: LMG 25358, LMG:25358, M. lappiensis, Mucilaginibacter lappiensis Mannisto et al. 2010, Mucilaginibacter sp. ANJLI2, Mucilaginibacter sp. MP601, Mucilaginibacter sp. RA1BR4, Sphingobacteriaceae bacterium ANJLI2, strain ANJLI2
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.