SIR89074.1 protein (Mucilaginibacter lappiensis)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

SIR89074.1

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (406 aa)

Predicted Functional Partners:

SIQ67007.1

0.965

SIS10944.1

0.941

SIQ66881.1

0.920

SIR76011.1

0.907

SIP98828.1

0.873

SIR89058.1

0.839

SIQ46616.1

0.832

SIP94594.1

0.827

SIQ47577.1

0.827

SIQ39290.1

0.797

Your Current Organism:

Mucilaginibacter lappiensis

NCBI taxonomy Id: 354630
Other names: LMG 25358, LMG:25358, M. lappiensis, Mucilaginibacter lappiensis Mannisto et al. 2010, Mucilaginibacter sp. ANJLI2, Mucilaginibacter sp. MP601, Mucilaginibacter sp. RA1BR4, Sphingobacteriaceae bacterium ANJLI2, strain ANJLI2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SIP94594.1	SIQ47577.1	SAMN05421821_101225	SAMN05421821_102557	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.	2-oxoisovalerate dehydrogenase E1 component.	0.999
SIP94594.1	SIQ66881.1	SAMN05421821_101225	SAMN05421821_103129	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.	PAS domain S-box-containing protein.	0.828
SIP94594.1	SIQ67007.1	SAMN05421821_101225	SAMN05421821_103132	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.	Signal transduction histidine kinase.	0.869
SIP94594.1	SIR76011.1	SAMN05421821_101225	SAMN05421821_111161	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.	PAS domain S-box-containing protein.	0.848
SIP94594.1	SIR89074.1	SAMN05421821_101225	SAMN05421821_114165	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	0.827
SIP98828.1	SIQ39290.1	SAMN05421821_101351	SAMN05421821_102363	PAS domain S-box-containing protein.	Response regulator receiver domain-containing protein.	0.761
SIP98828.1	SIQ46616.1	SAMN05421821_101351	SAMN05421821_102536	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, CheB/CheR fusion protein.	0.989
SIP98828.1	SIQ66881.1	SAMN05421821_101351	SAMN05421821_103129	PAS domain S-box-containing protein.	PAS domain S-box-containing protein.	0.999
SIP98828.1	SIQ67007.1	SAMN05421821_101351	SAMN05421821_103132	PAS domain S-box-containing protein.	Signal transduction histidine kinase.	0.999
SIP98828.1	SIR76011.1	SAMN05421821_101351	SAMN05421821_111161	PAS domain S-box-containing protein.	PAS domain S-box-containing protein.	0.999
SIP98828.1	SIR89074.1	SAMN05421821_101351	SAMN05421821_114165	PAS domain S-box-containing protein.	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	0.873
SIP98828.1	SIS10944.1	SAMN05421821_101351	SAMN05421821_12714	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, CheB/CheR fusion protein.	0.999
SIQ39290.1	SIP98828.1	SAMN05421821_102363	SAMN05421821_101351	Response regulator receiver domain-containing protein.	PAS domain S-box-containing protein.	0.761
SIQ39290.1	SIQ46616.1	SAMN05421821_102363	SAMN05421821_102536	Response regulator receiver domain-containing protein.	Two-component system, chemotaxis family, CheB/CheR fusion protein.	0.869
SIQ39290.1	SIQ66881.1	SAMN05421821_102363	SAMN05421821_103129	Response regulator receiver domain-containing protein.	PAS domain S-box-containing protein.	0.771
SIQ39290.1	SIQ67007.1	SAMN05421821_102363	SAMN05421821_103132	Response regulator receiver domain-containing protein.	Signal transduction histidine kinase.	0.850
SIQ39290.1	SIR76011.1	SAMN05421821_102363	SAMN05421821_111161	Response regulator receiver domain-containing protein.	PAS domain S-box-containing protein.	0.838
SIQ39290.1	SIR89074.1	SAMN05421821_102363	SAMN05421821_114165	Response regulator receiver domain-containing protein.	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	0.797
SIQ39290.1	SIS10944.1	SAMN05421821_102363	SAMN05421821_12714	Response regulator receiver domain-containing protein.	Two-component system, chemotaxis family, CheB/CheR fusion protein.	0.916
SIQ46616.1	SIP98828.1	SAMN05421821_102536	SAMN05421821_101351	Two-component system, chemotaxis family, CheB/CheR fusion protein.	PAS domain S-box-containing protein.	0.989

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Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.941

expected number of edges:

11

PPI enrichment p-value:

4.42e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006260

DNA replication

3 of 29

1.48

0.7

0.0344

GO:0006259

DNA metabolic process

5 of 116

1.1

0.61

0.0302

GO:0090304

Nucleic acid metabolic process

6 of 272

0.81

0.47

0.0344

GO:0046483

Heterocycle metabolic process

8 of 503

0.66

0.41

0.0302

GO:1901360

Organic cyclic compound metabolic process

8 of 524

0.65

0.4

0.0302

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030894

Replisome

4 of 9

2.11

2.58

5.87e-06

GO:0043590

Bacterial nucleoid

2 of 6

1.98

1.23

0.0041

GO:0032991

Protein-containing complex

5 of 156

0.97

0.76

0.0024

GO:0005622

Intracellular anatomical structure

8 of 961

0.38

0.27

0.0415

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3344

Mixed, incl. Smr domain, and RuvB-like P-loop domain

5 of 5

2.46

3.87

3.04e-08

CL:723

3-5 exonuclease activity, and DNA damage sensor activity

3 of 10

1.94

1.41

0.0016

CL:733

Bacterial nucleoid, and Rad50/SbcC-type AAA domain

2 of 5

2.06

0.9

0.0205

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03030

DNA replication

3 of 25

1.54

0.92

0.0114

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005694

Chromosome

4 of 24

1.68

1.57

0.00034

GOCC:0043590

Bacterial nucleoid

2 of 8

1.86

0.72

0.0428

GOCC:0030894

Replisome

2 of 9

1.81

0.71

0.0428

GOCC:0043229

Intracellular organelle

5 of 272

0.73

0.41

0.0457

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