STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)    
Predicted Functional Partners:
SIP93995.1
L-proline dehydrogenase.
   
 0.929
SIP90272.1
4-hydroxyproline epimerase; Belongs to the proline racemase family.
    
 0.913
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.898
SIR97390.1
Delta-1-pyrroline-5-carboxylate dehydrogenase.
   
 
 0.898
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
     
 0.872
SIP90572.1
Proline iminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
    
  0.739
SIR51347.1
Prolinase. Serine peptidase. MEROPS family S33.
    
  0.739
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.680
SIS10553.1
Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.598
SIS11031.1
D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.591
Your Current Organism:
Mucilaginibacter lappiensis
NCBI taxonomy Id: 354630
Other names: LMG 25358, LMG:25358, M. lappiensis, Mucilaginibacter lappiensis Mannisto et al. 2010, Mucilaginibacter sp. ANJLI2, Mucilaginibacter sp. MP601, Mucilaginibacter sp. RA1BR4, Sphingobacteriaceae bacterium ANJLI2, strain ANJLI2
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