| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEQ06985.1 | SEQ07003.1 | SAMN03080615_00271 | SAMN03080615_00272 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase expression/formation protein HypC. | 0.975 |
| SEQ06985.1 | SEQ07022.1 | SAMN03080615_00271 | SAMN03080615_00273 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | 0.975 |
| SEQ06985.1 | SEQ07036.1 | SAMN03080615_00271 | SAMN03080615_00274 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase expression/formation protein HypE. | 0.995 |
| SEQ06985.1 | SEQ10506.1 | SAMN03080615_00271 | SAMN03080615_00443 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase large subunit. | 0.739 |
| SEQ06985.1 | SEQ41568.1 | SAMN03080615_00271 | SAMN03080615_01448 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase nickel incorporation protein HypB. | 0.831 |
| SEQ06985.1 | SEQ41728.1 | SAMN03080615_00271 | SAMN03080615_01455 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase expression/formation protein HypC. | 0.430 |
| SEQ06985.1 | SEQ41832.1 | SAMN03080615_00271 | SAMN03080615_01459 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.576 |
| SEQ06985.1 | SEQ50979.1 | SAMN03080615_00271 | SAMN03080615_01759 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | NAD-reducing hydrogenase small subunit. | 0.762 |
| SEQ06985.1 | SEQ50999.1 | SAMN03080615_00271 | SAMN03080615_01760 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | NAD(P)-dependent nickel-iron dehydrogenase catalytic subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.816 |
| SEQ06985.1 | hypA | SAMN03080615_00271 | SAMN03080615_01449 | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.851 |
| SEQ07003.1 | SEQ06985.1 | SAMN03080615_00272 | SAMN03080615_00271 | Hydrogenase expression/formation protein HypC. | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.975 |
| SEQ07003.1 | SEQ07022.1 | SAMN03080615_00272 | SAMN03080615_00273 | Hydrogenase expression/formation protein HypC. | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | 0.998 |
| SEQ07003.1 | SEQ07036.1 | SAMN03080615_00272 | SAMN03080615_00274 | Hydrogenase expression/formation protein HypC. | Hydrogenase expression/formation protein HypE. | 0.994 |
| SEQ07003.1 | SEQ10506.1 | SAMN03080615_00272 | SAMN03080615_00443 | Hydrogenase expression/formation protein HypC. | Hydrogenase large subunit. | 0.808 |
| SEQ07003.1 | SEQ41568.1 | SAMN03080615_00272 | SAMN03080615_01448 | Hydrogenase expression/formation protein HypC. | Hydrogenase nickel incorporation protein HypB. | 0.931 |
| SEQ07003.1 | SEQ41832.1 | SAMN03080615_00272 | SAMN03080615_01459 | Hydrogenase expression/formation protein HypC. | Hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.616 |
| SEQ07003.1 | SEQ50979.1 | SAMN03080615_00272 | SAMN03080615_01759 | Hydrogenase expression/formation protein HypC. | NAD-reducing hydrogenase small subunit. | 0.735 |
| SEQ07003.1 | SEQ50999.1 | SAMN03080615_00272 | SAMN03080615_01760 | Hydrogenase expression/formation protein HypC. | NAD(P)-dependent nickel-iron dehydrogenase catalytic subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.780 |
| SEQ07003.1 | hypA | SAMN03080615_00272 | SAMN03080615_01449 | Hydrogenase expression/formation protein HypC. | Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.866 |
| SEQ07022.1 | SEQ06985.1 | SAMN03080615_00273 | SAMN03080615_00271 | Hydrogenase expression/formation protein HypD; Belongs to the HypD family. | Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.975 |
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