| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEQ04445.1 | SEQ28825.1 | SAMN03080615_00155 | SAMN03080615_01059 | PAS domain S-box-containing protein. | Glutamate synthase (NADPH/NADH) large chain. | 0.614 |
| SEQ04445.1 | SEQ84776.1 | SAMN03080615_00155 | SAMN03080615_02930 | PAS domain S-box-containing protein. | Glutamine synthetase. | 0.442 |
| SEQ04445.1 | glnE | SAMN03080615_00155 | SAMN03080615_01004 | PAS domain S-box-containing protein. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.524 |
| SEQ07366.1 | argA | SAMN03080615_00294 | SAMN03080615_01000 | ATP-dependent helicase HrpA. | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.401 |
| SEQ07366.1 | glnE | SAMN03080615_00294 | SAMN03080615_01004 | ATP-dependent helicase HrpA. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.621 |
| SEQ27446.1 | argA | SAMN03080615_01003 | SAMN03080615_01000 | Hypothetical protein. | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.539 |
| SEQ27446.1 | glnE | SAMN03080615_01003 | SAMN03080615_01004 | Hypothetical protein. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.462 |
| SEQ28825.1 | SEQ04445.1 | SAMN03080615_01059 | SAMN03080615_00155 | Glutamate synthase (NADPH/NADH) large chain. | PAS domain S-box-containing protein. | 0.614 |
| SEQ28825.1 | SEQ84776.1 | SAMN03080615_01059 | SAMN03080615_02930 | Glutamate synthase (NADPH/NADH) large chain. | Glutamine synthetase. | 0.940 |
| SEQ28825.1 | argA | SAMN03080615_01059 | SAMN03080615_01000 | Glutamate synthase (NADPH/NADH) large chain. | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.730 |
| SEQ28825.1 | aroA | SAMN03080615_01059 | SAMN03080615_02942 | Glutamate synthase (NADPH/NADH) large chain. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.608 |
| SEQ28825.1 | glnD | SAMN03080615_01059 | SAMN03080615_03416 | Glutamate synthase (NADPH/NADH) large chain. | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.682 |
| SEQ28825.1 | glnE | SAMN03080615_01059 | SAMN03080615_01004 | Glutamate synthase (NADPH/NADH) large chain. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.578 |
| SEQ31286.1 | glnE | SAMN03080615_01167 | SAMN03080615_01004 | ABC-type uncharacterized transport system, permease component. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.494 |
| SEQ67925.1 | glnE | SAMN03080615_02337 | SAMN03080615_01004 | Peroxiredoxin Q/BCP. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.473 |
| SEQ84776.1 | SEQ04445.1 | SAMN03080615_02930 | SAMN03080615_00155 | Glutamine synthetase. | PAS domain S-box-containing protein. | 0.442 |
| SEQ84776.1 | SEQ28825.1 | SAMN03080615_02930 | SAMN03080615_01059 | Glutamine synthetase. | Glutamate synthase (NADPH/NADH) large chain. | 0.940 |
| SEQ84776.1 | glnE | SAMN03080615_02930 | SAMN03080615_01004 | Glutamine synthetase. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.728 |
| argA | SEQ07366.1 | SAMN03080615_01000 | SAMN03080615_00294 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | ATP-dependent helicase HrpA. | 0.401 |
| argA | SEQ27446.1 | SAMN03080615_01000 | SAMN03080615_01003 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Hypothetical protein. | 0.539 |
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