| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEQ42691.1 | SEQ95078.1 | SAMN03080615_01500 | SAMN03080615_03357 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | Acyl transferase domain-containing protein. | 0.644 |
| SEQ42691.1 | dnaJ | SAMN03080615_01500 | SAMN03080615_01140 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.994 |
| SEQ42691.1 | groL | SAMN03080615_01500 | SAMN03080615_02103 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.954 |
| SEQ42691.1 | grpE | SAMN03080615_01500 | SAMN03080615_01138 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.990 |
| SEQ42691.1 | htpG | SAMN03080615_01500 | SAMN03080615_00437 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.981 |
| SEQ42691.1 | rpoH | SAMN03080615_01500 | SAMN03080615_00932 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.689 |
| SEQ50934.1 | SEQ95078.1 | SAMN03080615_01757 | SAMN03080615_03357 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit. | Acyl transferase domain-containing protein. | 0.999 |
| SEQ50934.1 | dnaJ | SAMN03080615_01757 | SAMN03080615_01140 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.899 |
| SEQ50934.1 | groL | SAMN03080615_01757 | SAMN03080615_02103 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.469 |
| SEQ95078.1 | SEQ42691.1 | SAMN03080615_03357 | SAMN03080615_01500 | Acyl transferase domain-containing protein. | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | 0.644 |
| SEQ95078.1 | SEQ50934.1 | SAMN03080615_03357 | SAMN03080615_01757 | Acyl transferase domain-containing protein. | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit. | 0.999 |
| SEQ95078.1 | dnaJ | SAMN03080615_03357 | SAMN03080615_01140 | Acyl transferase domain-containing protein. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.907 |
| SEQ95078.1 | dnaK | SAMN03080615_03357 | SAMN03080615_01139 | Acyl transferase domain-containing protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.644 |
| SEQ95078.1 | groL | SAMN03080615_03357 | SAMN03080615_02103 | Acyl transferase domain-containing protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.638 |
| SEQ95078.1 | grpE | SAMN03080615_03357 | SAMN03080615_01138 | Acyl transferase domain-containing protein. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.448 |
| SEQ95078.1 | hscA | SAMN03080615_03357 | SAMN03080615_03769 | Acyl transferase domain-containing protein. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.644 |
| SEQ95078.1 | htpG | SAMN03080615_03357 | SAMN03080615_00437 | Acyl transferase domain-containing protein. | Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. | 0.743 |
| SEQ95078.1 | rpoH | SAMN03080615_03357 | SAMN03080615_00932 | Acyl transferase domain-containing protein. | RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.613 |
| dapB | dnaJ | SAMN03080615_01142 | SAMN03080615_01140 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.884 |
| dapB | dnaK | SAMN03080615_01142 | SAMN03080615_01139 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.478 |
STRING v12.5 is now available!
