close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEQ47428.1Iron-sulfur cluster assembly protein; Belongs to the HesB/IscA family. (107 aa)    
Predicted Functional Partners:
SEQ47440.1
Modular FeS cluster scaffolding protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
 
 
 0.990
SEQ47459.1
Cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
 
  
 0.853
SEQ67351.1
Cysteine desulfurase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.671
SER05637.1
Nitrogen fixation protein NifU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
  
 0.668
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
 
 
 0.634
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
  
 0.615
hscB
Co-chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.608
SEQ47294.1
Probable nitrogen fixation protein.
 
  
 0.598
SER19713.1
DnaJ like chaperone protein.
  
 
 0.575
SER20092.1
Monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.548
Your Current Organism:
Amphritea atlantica
NCBI taxonomy Id: 355243
Other names: A. atlantica, Amphritea atlantica Gartner et al. 2008 emend. Jang et al. 2015, DSM 18887, LMG 24143, LMG:24143, gamma proteobacterium M41, strain M41
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.