node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEQ01015.1 | SEQ21733.1 | SAMN03080615_00001 | SAMN03080615_00743 | 4-hydroxy-2-oxovalerate aldolase. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.587 |
SEQ01015.1 | SEQ67260.1 | SAMN03080615_00001 | SAMN03080615_02300 | 4-hydroxy-2-oxovalerate aldolase. | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | 0.795 |
SEQ01015.1 | dnaA | SAMN03080615_00001 | SAMN03080615_00742 | 4-hydroxy-2-oxovalerate aldolase. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.795 |
SEQ01015.1 | polA | SAMN03080615_00001 | SAMN03080615_00660 | 4-hydroxy-2-oxovalerate aldolase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.800 |
SEQ01015.1 | rpmE | SAMN03080615_00001 | SAMN03080615_01048 | 4-hydroxy-2-oxovalerate aldolase. | LSU ribosomal protein L31P; Binds the 23S rRNA. | 0.543 |
SEQ21733.1 | SEQ01015.1 | SAMN03080615_00743 | SAMN03080615_00001 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 4-hydroxy-2-oxovalerate aldolase. | 0.587 |
SEQ21733.1 | SEQ67260.1 | SAMN03080615_00743 | SAMN03080615_02300 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | 0.989 |
SEQ21733.1 | SEQ86754.1 | SAMN03080615_00743 | SAMN03080615_03047 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.592 |
SEQ21733.1 | dnaA | SAMN03080615_00743 | SAMN03080615_00742 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.998 |
SEQ21733.1 | polA | SAMN03080615_00743 | SAMN03080615_00660 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
SEQ21733.1 | recF | SAMN03080615_00743 | SAMN03080615_00744 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.973 |
SEQ67231.1 | SEQ67238.1 | SAMN03080615_02298 | SAMN03080615_02299 | Hypothetical protein. | Predicted PurR-regulated permease PerM. | 0.722 |
SEQ67231.1 | SEQ67260.1 | SAMN03080615_02298 | SAMN03080615_02300 | Hypothetical protein. | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | 0.617 |
SEQ67238.1 | SEQ67231.1 | SAMN03080615_02299 | SAMN03080615_02298 | Predicted PurR-regulated permease PerM. | Hypothetical protein. | 0.722 |
SEQ67238.1 | SEQ67260.1 | SAMN03080615_02299 | SAMN03080615_02300 | Predicted PurR-regulated permease PerM. | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | 0.660 |
SEQ67238.1 | SEQ67275.1 | SAMN03080615_02299 | SAMN03080615_02301 | Predicted PurR-regulated permease PerM. | Hypothetical protein. | 0.445 |
SEQ67260.1 | SEQ01015.1 | SAMN03080615_02300 | SAMN03080615_00001 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | 4-hydroxy-2-oxovalerate aldolase. | 0.795 |
SEQ67260.1 | SEQ21733.1 | SAMN03080615_02300 | SAMN03080615_00743 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.989 |
SEQ67260.1 | SEQ67231.1 | SAMN03080615_02300 | SAMN03080615_02298 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | Hypothetical protein. | 0.617 |
SEQ67260.1 | SEQ67238.1 | SAMN03080615_02300 | SAMN03080615_02299 | Regulatory inactivation of DnaA Hda protein; Belongs to the DnaA family. HdA subfamily. | Predicted PurR-regulated permease PerM. | 0.660 |