STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEQ99492.14-hydroxy-2-oxovalerate/4-hydroxy-2-oxohexanoate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (347 aa)    
Predicted Functional Partners:
SEQ99521.1
Acetaldehyde/propanal dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 0.992
SEQ01041.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 0.972
SER08606.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 0.972
SEQ97517.1
Acetaldehyde dehydrogenase (acetylating).
 
 0.944
SEQ70486.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 
 0.934
SEQ99553.1
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase.
 
 
  0.905
SEQ99484.1
2-oxo-3-hexenedioate decarboxylase.
 
 
  0.867
SEQ01015.1
4-hydroxy-2-oxovalerate aldolase.
 
 
0.793
SER20227.1
Urea carboxylase.
  
 
 0.789
SEQ01068.1
2-keto-4-pentenoate hydratase.
 
 
  0.782
Your Current Organism:
Amphritea atlantica
NCBI taxonomy Id: 355243
Other names: A. atlantica, Amphritea atlantica Gartner et al. 2008 emend. Jang et al. 2015, DSM 18887, LMG 24143, LMG:24143, gamma proteobacterium M41, strain M41
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