| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEQ61752.1 | SER12421.1 | SAMN03080615_02148 | SAMN03080615_03993 | Ribosome-associated protein; Belongs to the UPF0307 family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.870 |
| SEQ61752.1 | obg | SAMN03080615_02148 | SAMN03080615_04016 | Ribosome-associated protein; Belongs to the UPF0307 family. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.769 |
| SEQ61752.1 | rplC | SAMN03080615_02148 | SAMN03080615_04071 | Ribosome-associated protein; Belongs to the UPF0307 family. | Large subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.796 |
| SEQ61752.1 | rplR | SAMN03080615_02148 | SAMN03080615_04055 | Ribosome-associated protein; Belongs to the UPF0307 family. | Large subunit ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.767 |
| SEQ61752.1 | rplS | SAMN03080615_02148 | SAMN03080615_01172 | Ribosome-associated protein; Belongs to the UPF0307 family. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.787 |
| SEQ61752.1 | rplT | SAMN03080615_02148 | SAMN03080615_01996 | Ribosome-associated protein; Belongs to the UPF0307 family. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.767 |
| SEQ61752.1 | rplU | SAMN03080615_02148 | SAMN03080615_04018 | Ribosome-associated protein; Belongs to the UPF0307 family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.772 |
| SEQ61752.1 | rsfS | SAMN03080615_02148 | SAMN03080615_04154 | Ribosome-associated protein; Belongs to the UPF0307 family. | Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.782 |
| SER12399.1 | SER12421.1 | SAMN03080615_03992 | SAMN03080615_03993 | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.928 |
| SER12421.1 | SEQ61752.1 | SAMN03080615_03993 | SAMN03080615_02148 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosome-associated protein; Belongs to the UPF0307 family. | 0.870 |
| SER12421.1 | SER12399.1 | SAMN03080615_03993 | SAMN03080615_03992 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.928 |
| SER12421.1 | mnmE | SAMN03080615_03993 | SAMN03080615_00738 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.867 |
| SER12421.1 | obg | SAMN03080615_03993 | SAMN03080615_04016 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.941 |
| SER12421.1 | rplC | SAMN03080615_03993 | SAMN03080615_04071 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Large subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.849 |
| SER12421.1 | rplR | SAMN03080615_03993 | SAMN03080615_04055 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Large subunit ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.861 |
| SER12421.1 | rplS | SAMN03080615_03993 | SAMN03080615_01172 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.870 |
| SER12421.1 | rplT | SAMN03080615_03993 | SAMN03080615_01996 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.864 |
| SER12421.1 | rplU | SAMN03080615_03993 | SAMN03080615_04018 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.868 |
| SER12421.1 | rsfS | SAMN03080615_03993 | SAMN03080615_04154 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.830 |
| mnmE | SER12421.1 | SAMN03080615_00738 | SAMN03080615_03993 | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.867 |
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