| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEQ86754.1 | SEQ95886.1 | SAMN03080615_03047 | SAMN03080615_03400 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase-3 subunit alpha. | 0.661 |
| SEQ86754.1 | SER13277.1 | SAMN03080615_03047 | SAMN03080615_04039 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.855 |
| SEQ86754.1 | dnaX | SAMN03080615_03047 | SAMN03080615_03596 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.927 |
| SEQ86754.1 | priA | SAMN03080615_03047 | SAMN03080615_01047 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.620 |
| SEQ86754.1 | rpsF | SAMN03080615_03047 | SAMN03080615_03050 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Small subunit ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.461 |
| SEQ86754.1 | topA | SAMN03080615_03047 | SAMN03080615_01290 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.670 |
| SEQ95886.1 | SEQ86754.1 | SAMN03080615_03400 | SAMN03080615_03047 | DNA polymerase-3 subunit alpha. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.661 |
| SEQ95886.1 | SER04824.1 | SAMN03080615_03400 | SAMN03080615_03724 | DNA polymerase-3 subunit alpha. | DNA polymerase III, chi subunit. | 0.985 |
| SEQ95886.1 | SER13277.1 | SAMN03080615_03400 | SAMN03080615_04039 | DNA polymerase-3 subunit alpha. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.962 |
| SEQ95886.1 | dnaX | SAMN03080615_03400 | SAMN03080615_03596 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.992 |
| SEQ95886.1 | rnhA | SAMN03080615_03400 | SAMN03080615_02363 | DNA polymerase-3 subunit alpha. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.610 |
| SEQ95886.1 | rpsB | SAMN03080615_03400 | SAMN03080615_03414 | DNA polymerase-3 subunit alpha. | Small subunit ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.656 |
| SEQ95886.1 | topA | SAMN03080615_03400 | SAMN03080615_01290 | DNA polymerase-3 subunit alpha. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.557 |
| SER04824.1 | SEQ95886.1 | SAMN03080615_03724 | SAMN03080615_03400 | DNA polymerase III, chi subunit. | DNA polymerase-3 subunit alpha. | 0.985 |
| SER04824.1 | SER13277.1 | SAMN03080615_03724 | SAMN03080615_04039 | DNA polymerase III, chi subunit. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.923 |
| SER04824.1 | dnaX | SAMN03080615_03724 | SAMN03080615_03596 | DNA polymerase III, chi subunit. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.987 |
| SER04824.1 | rnhA | SAMN03080615_03724 | SAMN03080615_02363 | DNA polymerase III, chi subunit. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.539 |
| SER04824.1 | topA | SAMN03080615_03724 | SAMN03080615_01290 | DNA polymerase III, chi subunit. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.472 |
| SER13277.1 | SEQ86754.1 | SAMN03080615_04039 | SAMN03080615_03047 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.855 |
| SER13277.1 | SEQ95886.1 | SAMN03080615_04039 | SAMN03080615_03400 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase-3 subunit alpha. | 0.962 |
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