STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ42_022372ATP-dependent DNA Helicase Q5-like protein. (1046 aa)    
Predicted Functional Partners:
APZ42_031912
Putative ATP-dependent RNA helicase DHX58.
   
 0.999
APZ42_020612
DNA replication ATP-dependent helicase/nuclease DNA2.
   
 0.907
APZ42_022013
DNA repair protein RAD52.
   
 0.904
APZ42_015463
Crossover junction endonuclease MUS81.
    
 0.902
APZ42_011513
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.881
APZ42_033992
Putative RecQ-mediated instability protein 1.
    
 0.878
APZ42_034386
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.860
APZ42_026490
ATM/Rad3 and Mei-41-like protein; Belongs to the PI3/PI4-kinase family.
   
 0.860
APZ42_018703
F-box DNA helicase 1.
  
 0.859
APZ42_033162
ResIII domain-containing protein.
  
 0.859
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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