node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APZ42_011513 | APZ42_015463 | A0A162SR63 | A0A162PHN8 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Crossover junction endonuclease MUS81. | 0.932 |
APZ42_011513 | APZ42_018703 | A0A162SR63 | A0A0N7ZPB5 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | F-box DNA helicase 1. | 0.674 |
APZ42_011513 | APZ42_020612 | A0A162SR63 | A0A162CC26 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA replication ATP-dependent helicase/nuclease DNA2. | 0.874 |
APZ42_011513 | APZ42_022013 | A0A162SR63 | A0A0P4Y4Y5 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA repair protein RAD52. | 0.880 |
APZ42_011513 | APZ42_022372 | A0A162SR63 | A0A0P5E3J2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent DNA Helicase Q5-like protein. | 0.881 |
APZ42_011513 | APZ42_026490 | A0A162SR63 | A0A162EDE1 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATM/Rad3 and Mei-41-like protein; Belongs to the PI3/PI4-kinase family. | 0.802 |
APZ42_011513 | APZ42_031912 | A0A162SR63 | A0A164ME63 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Putative ATP-dependent RNA helicase DHX58. | 0.999 |
APZ42_011513 | APZ42_033162 | A0A162SR63 | A0A164LCB6 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ResIII domain-containing protein. | 0.674 |
APZ42_011513 | APZ42_033992 | A0A162SR63 | A0A164KJY7 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Putative RecQ-mediated instability protein 1. | 0.998 |
APZ42_011513 | APZ42_034386 | A0A162SR63 | A0A0N8CUT7 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.826 |
APZ42_015463 | APZ42_011513 | A0A162PHN8 | A0A162SR63 | Crossover junction endonuclease MUS81. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.932 |
APZ42_015463 | APZ42_018703 | A0A162PHN8 | A0A0N7ZPB5 | Crossover junction endonuclease MUS81. | F-box DNA helicase 1. | 0.750 |
APZ42_015463 | APZ42_020612 | A0A162PHN8 | A0A162CC26 | Crossover junction endonuclease MUS81. | DNA replication ATP-dependent helicase/nuclease DNA2. | 0.874 |
APZ42_015463 | APZ42_022013 | A0A162PHN8 | A0A0P4Y4Y5 | Crossover junction endonuclease MUS81. | DNA repair protein RAD52. | 0.947 |
APZ42_015463 | APZ42_022372 | A0A162PHN8 | A0A0P5E3J2 | Crossover junction endonuclease MUS81. | ATP-dependent DNA Helicase Q5-like protein. | 0.902 |
APZ42_015463 | APZ42_026490 | A0A162PHN8 | A0A162EDE1 | Crossover junction endonuclease MUS81. | ATM/Rad3 and Mei-41-like protein; Belongs to the PI3/PI4-kinase family. | 0.868 |
APZ42_015463 | APZ42_031912 | A0A162PHN8 | A0A164ME63 | Crossover junction endonuclease MUS81. | Putative ATP-dependent RNA helicase DHX58. | 0.999 |
APZ42_015463 | APZ42_033162 | A0A162PHN8 | A0A164LCB6 | Crossover junction endonuclease MUS81. | ResIII domain-containing protein. | 0.750 |
APZ42_015463 | APZ42_033992 | A0A162PHN8 | A0A164KJY7 | Crossover junction endonuclease MUS81. | Putative RecQ-mediated instability protein 1. | 0.934 |
APZ42_015463 | APZ42_034386 | A0A162PHN8 | A0A0N8CUT7 | Crossover junction endonuclease MUS81. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.849 |