STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ42_004255Actin, alpha skeletal muscle. (294 aa)    
Predicted Functional Partners:
APZ42_032694
Uncharacterized protein.
    
 0.946
APZ42_024542
Brahma associated protein 55kD; Belongs to the actin family.
  
 
0.892
APZ42_028881
Dynactin subunit 2.
    
 0.888
APZ42_034395
Actin-related protein 10; Belongs to the actin family.
    
0.882
APZ42_014982
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
  
 
0.881
APZ42_011508
Actin-related protein 3; Belongs to the actin family.
   
0.879
APZ42_011061
Myosin essential light chain.
   
 0.873
APZ42_024488
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
    
 0.873
EOG090X05RK
Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.870
APZ42_030076
ATP-dependent Helicase brm.
    
 0.866
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.