STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ42_013795Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1260 aa)    
Predicted Functional Partners:
APZ42_019649
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.993
APZ42_018609
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.969
APZ42_028980
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.968
APZ42_020866
10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
   
 0.967
APZ42_027308
Bifunctional dihydrofolate reductase-thymidylate synthase.
  
 
 0.960
APZ42_015422
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
     
 0.956
APZ42_013661
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
     
 0.956
APZ42_030079
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.955
APZ42_003014
Putative 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
  
 
 0.953
APZ42_013400
Formimidoyltransferase-cyclodeaminase.
  
 
 0.948
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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