STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ42_021137Putative Ribonuclease H1. (402 aa)    
Predicted Functional Partners:
APZ42_027308
Bifunctional dihydrofolate reductase-thymidylate synthase.
    
 0.815
APZ42_018992
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
 
 0.733
APZ42_018111
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.704
APZ42_023272
Nucleoside diphosphate-linked moiety X motif.
    
  0.700
APZ42_013303
Phosphoglycerate kinase.
    
  0.699
APZ42_018388
Alpha-enolase.
    
  0.689
EOG090X0O5J
Single-stranded DNA-binding protein, mitochondrial.
   
 
 0.685
APZ42_025332
Thymidylate kinase.
  
 
 0.681
APZ42_026860
Iodotyrosine deiodinase 1.
    
 0.651
Fen1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.642
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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