APZ42_012467 protein (Daphnia magna) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

APZ42_012467

Down syndrome cell adhesion molecule 4. (1967 aa)

Predicted Functional Partners:

APZ42_018038

0.766

APZ42_033871

0.751

APZ42_019374

0.751

APZ42_017757

0.751

APZ42_024428

0.664

APZ42_026174

0.619

APZ42_019735

0.619

APZ42_017808

0.619

APZ42_021232

0.616

APZ42_028532

0.599

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_012467	APZ42_017757	A0A162RW16	A0A164ZLB7	Down syndrome cell adhesion molecule 4.	Putative Fibronectin type-III domain-containing protein 3A.	0.751
APZ42_012467	APZ42_017808	A0A162RW16	A0A164ZK23	Down syndrome cell adhesion molecule 4.	Relaxin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.619
APZ42_012467	APZ42_018038	A0A162RW16	A0A164ZHV0	Down syndrome cell adhesion molecule 4.	Inactive tyrosine-protein kinase 7.	0.766
APZ42_012467	APZ42_019374	A0A162RW16	A0A164YD89	Down syndrome cell adhesion molecule 4.	Uncharacterized protein.	0.751
APZ42_012467	APZ42_019735	A0A162RW16	A0A164XNT7	Down syndrome cell adhesion molecule 4.	Relaxin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.619
APZ42_012467	APZ42_021232	A0A162RW16	A0A164WUR8	Down syndrome cell adhesion molecule 4.	Neogenin.	0.616
APZ42_012467	APZ42_024428	A0A162RW16	A0A164U1Q7	Down syndrome cell adhesion molecule 4.	Netrin-1.	0.664
APZ42_012467	APZ42_026174	A0A162RW16	A0A164SFE0	Down syndrome cell adhesion molecule 4.	Relaxin receptor 1.	0.619
APZ42_012467	APZ42_028532	A0A162RW16	A0A0P5ZJC7	Down syndrome cell adhesion molecule 4.	Complement C1q tumor necrosis factor-related 7-like protein.	0.599
APZ42_012467	APZ42_033871	A0A162RW16	A0A164KNT3	Down syndrome cell adhesion molecule 4.	Leucine-rich repeat kinase.	0.751
APZ42_017757	APZ42_012467	A0A164ZLB7	A0A162RW16	Putative Fibronectin type-III domain-containing protein 3A.	Down syndrome cell adhesion molecule 4.	0.751
APZ42_017757	APZ42_017808	A0A164ZLB7	A0A164ZK23	Putative Fibronectin type-III domain-containing protein 3A.	Relaxin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.742
APZ42_017757	APZ42_018038	A0A164ZLB7	A0A164ZHV0	Putative Fibronectin type-III domain-containing protein 3A.	Inactive tyrosine-protein kinase 7.	0.915
APZ42_017757	APZ42_019374	A0A164ZLB7	A0A164YD89	Putative Fibronectin type-III domain-containing protein 3A.	Uncharacterized protein.	0.888
APZ42_017757	APZ42_019735	A0A164ZLB7	A0A164XNT7	Putative Fibronectin type-III domain-containing protein 3A.	Relaxin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.742
APZ42_017757	APZ42_021232	A0A164ZLB7	A0A164WUR8	Putative Fibronectin type-III domain-containing protein 3A.	Neogenin.	0.550
APZ42_017757	APZ42_024428	A0A164ZLB7	A0A164U1Q7	Putative Fibronectin type-III domain-containing protein 3A.	Netrin-1.	0.690
APZ42_017757	APZ42_026174	A0A164ZLB7	A0A164SFE0	Putative Fibronectin type-III domain-containing protein 3A.	Relaxin receptor 1.	0.742
APZ42_017757	APZ42_028532	A0A164ZLB7	A0A0P5ZJC7	Putative Fibronectin type-III domain-containing protein 3A.	Complement C1q tumor necrosis factor-related 7-like protein.	0.918
APZ42_017757	APZ42_033871	A0A164ZLB7	A0A164KNT3	Putative Fibronectin type-III domain-containing protein 3A.	Leucine-rich repeat kinase.	0.998

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Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.856

expected number of edges:

33

PPI enrichment p-value:

0.959

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2713

Alpha/beta hydrolase fold-1

4 of 6

2.57

3.35

1.13e-06

CL:1085

Phosphopantetheine attachment site, and Thioesterase domain

2 of 10

2.04

0.79

0.0417

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031975

Envelope

4 of 85

1.42

1.1

0.0033

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

3 of 47

1.55

0.9

0.0158

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00561

Alpha/beta hydrolase fold

3 of 22

1.88

1.19

0.0061

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000073

Alpha/beta hydrolase fold-1

4 of 22

2.0

2.04

0.00012

IPR032821

Polyketide synthase, C-terminal extension

3 of 16

2.02

1.4

0.0028

IPR013968

Polyketide synthase, ketoreductase domain

3 of 15

2.04

1.4

0.0028

IPR016036

Malonyl-CoA ACP transacylase, ACP-binding

3 of 17

1.99

1.39

0.0028

IPR014043

Acyl transferase

3 of 17

1.99

1.39

0.0028

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

3 of 13

2.11

1.88

0.00034

SM00827

Acyl transferase domain in polyketide synthase (PKS) enzymes.

3 of 15

2.04

1.85

0.00034

SM00823

Phosphopantetheine attachment site

3 of 16

2.02

1.84

0.00034

SM00826

PKS_DH

2 of 4

2.44

1.61

0.0016

SM00825

Beta-ketoacyl synthase

2 of 12

1.96

1.16

0.0078

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