STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ42_009724RT_RNaseH domain-containing protein. (313 aa)    
Predicted Functional Partners:
APZ42_031912
Putative ATP-dependent RNA helicase DHX58.
    
  0.797
APZ42_010980
Protein lin-52.
    
 0.574
APZ42_031506
Lin-54.
    
 0.569
APZ42_011612
Putative Myb-related protein B.
    
  0.561
APZ42_017650
Histone-binding protein RBBP4.
    
 0.560
APZ42_025541
Protein lin-9.
    
 0.557
APZ42_024857
Receptor protein-tyrosine kinase.
    
  0.553
APZ42_030620
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
  0.520
APZ42_011418
Replication protein A 32 kDa subunit.
    
  0.518
APZ42_002734
Pro-neuregulin-2, membrane-bound.
    
  0.470
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.