STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ42_007443Ubiquitin-protein ligase E3C. (154 aa)    
Predicted Functional Partners:
APZ42_015304
Ubiquitin-protein ligase E3B.
 
 
 
 0.645
APZ42_027416
26S proteasome non-ATPase regulatory subunit 14.
    
 
 0.633
APZ42_005840
Polyubiquitin-B.
    
  0.631
APZ42_021729
Polyubiquitin-B.
    
  0.631
APZ42_031545
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 
 0.536
APZ42_030968
Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.535
APZ42_026496
Nedd8-activating enzyme E1 catalytic subunit.
   
 
  0.528
APZ42_027865
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.508
APZ42_014672
Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.487
APZ42_014846
Ubiquitin-conjugating enzyme E2 D4.
    
 
 0.487
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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