STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ42_032189Numb-associated kinase. (400 aa)    
Predicted Functional Partners:
APZ42_028960
Cyclin-G-associated kinase.
   
 0.988
APZ42_026055
RalBP1-associated Eps domain-containing protein.
    
 0.820
APZ42_020788
AP complex subunit beta.
    
 0.806
APZ42_029329
Putative Huntingtin interacting protein 1.
    
 0.743
APZ42_003320
Putative Huntingtin-interacting protein 1.
    
 0.743
APZ42_021443
AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
    
 0.729
APZ42_018911
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.727
APZ42_015608
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.720
APZ42_011811
Putative Spindle assembly abnormal 4.
    
 0.718
APZ42_022186
Epidermal growth factor receptor substrate 15 1-like protein.
    
 0.718
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.