STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ42_029283Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (366 aa)    
Predicted Functional Partners:
APZ42_026767
Nicastrin.
   
 0.984
APZ42_019025
Gamma-secretase subunit PEN-2.
    
 0.980
APZ42_023831
Gamma-secretase subunit Aph-1b.
   
 0.979
APZ42_023676
Putative Transcription coactivator armadillo.
    
 0.891
APZ42_031668
Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily.
    
 0.879
APZ42_002723
Putative Transcription coactivator armadillo.
    
 0.824
APZ42_012052
Uncharacterized protein.
    
 0.791
APZ42_012042
Uncharacterized protein.
    
 0.791
APZ42_033022
Uncharacterized protein.
    
 0.783
APZ42_031983
Uncharacterized protein.
    
 0.783
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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