STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ42_020710Putative EH domain-containing protein 2. (410 aa)    
Predicted Functional Partners:
APZ42_023754
Rabenosyn-5.
    
 0.844
APZ42_018911
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.733
EOG090X0665
Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
    
 
 0.716
APZ42_015608
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
    
 0.700
APZ42_021443
AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
    
 0.686
APZ42_020216
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.679
APZ42_020788
AP complex subunit beta.
     
 0.635
APZ42_024908
AP-3 complex subunit delta-1.
    
 0.612
APZ42_024201
AP-1 complex subunit gamma.
    
  0.590
EOG090X03QA
Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family.
     
 0.547
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.