STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1I8PUQ9PX domain-containing protein. (169 aa)    
Predicted Functional Partners:
A0A1I8NYJ6
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.991
A0A1I8PVE8
Uncharacterized protein.
    
 0.984
A0A1I8NMV0
VWFA domain-containing protein.
    
 0.980
A0A1I8PS91
Uncharacterized protein.
    
 0.918
A0A1I8PJ86
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.912
A0A1I8NW63
Uncharacterized protein.
     
 0.877
A0A1I8Q778
USP domain-containing protein; Belongs to the peptidase C19 family.
    
 0.796
A0A1I8PQT3
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
    
 
 0.693
A0A1I8PMK6
Uncharacterized protein.
     
 0.684
A0A1I8PDZ4
PX domain-containing protein.
   
 
0.649
Your Current Organism:
Stomoxys calcitrans
NCBI taxonomy Id: 35570
Other names: S. calcitrans, Stomoxis calcitrans, biting house fly, stable fly
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