STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTI12_AA548690A_deaminase domain-containing protein. (73 aa)    
Predicted Functional Partners:
PURA
Adenylosuccinate synthetase, chloroplastic; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.944
CTI12_AA408590
Adenine phosphoribosyltransferase 5.
   
 0.943
CTI12_AA250780
Aldolase-type TIM barrel family protein.
  
 0.943
CTI12_AA043090
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 0.943
CTI12_AA292230
Adenine phosphoribosyl transferase.
   
 0.941
CTI12_AA008220
Adenine phosphoribosyl transferase.
   
 0.941
CTI12_AA034300
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
 0.938
CTI12_AA384940
Adenine phosphoribosyl transferase, Phosphoribosyltransferase-like protein.
   
 0.937
CTI12_AA489060
Hypoxanthine phosphoribosyl transferase.
     
 0.936
CTI12_AA038610
Adenosine kinase 2.
    
 0.934
Your Current Organism:
Artemisia annua
NCBI taxonomy Id: 35608
Other names: A. annua, Artemisia annua L., sweet Annie, sweet wormwood
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.