STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTI12_AA527090Alkyl transferase; Belongs to the UPP synthase family. (302 aa)    
Predicted Functional Partners:
CTI12_AA204530
Undecaprenyl pyrophosphate synthetase family protein.
   
 0.968
CTI12_AA387720
Undecaprenyl pyrophosphate synthetase family protein.
   
 0.968
CTI12_AA543340
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
     
 0.925
CTI12_AA419400
Geranylgeranyl reductase; Belongs to the FPP/GGPP synthase family.
  
 
 0.913
CTI12_AA226570
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
  
 
 0.910
CTI12_AA224510
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.903
FPS1
Farnesyl pyrophosphate synthase; Involved in the biosynthesis of the antimalarial endoperoxide artemisinin. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. Promotes anti-malarial and antimicrobial (toward Gram-positive bacteria B.subtilis and S.aureus) activities of plant crude extract probably by triggering artemisinin levels. Belongs to the FPP/GGPP synthase family.
  
 
 0.903
CTI12_AA613010
Squalene/phytoene synthase.
   
 
 0.897
CTI12_AA414190
Squalene/phytoene synthase.
   
 
 0.897
CTI12_AA086500
Squalene/phytoene synthase.
   
 
 0.897
Your Current Organism:
Artemisia annua
NCBI taxonomy Id: 35608
Other names: A. annua, Artemisia annua L., sweet Annie, sweet wormwood
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