STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOVF_168600Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (374 aa)    
Predicted Functional Partners:
SOVF_133090
Uncharacterized protein.
    
  0.809
SOVF_203170
Uncharacterized protein; Belongs to the peptidase C1 family.
  
 0.708
SOVF_110050
Aminotran_1_2 domain-containing protein.
      
 0.607
SOVF_130600
Aminotran_1_2 domain-containing protein.
      
 0.605
SOVF_186240
Calreticulin.
   
  
 0.600
SOVF_137800
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
      
 0.581
THI1
Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]
      
 0.571
SOVF_117520
Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
      
 0.562
SOVF_150630
Uncharacterized protein; Belongs to the peptidase C1 family.
  
0.542
SOVF_027660
Uncharacterized protein; Belongs to the peptidase C1 family.
  
0.542
Your Current Organism:
Spinacia oleracea
NCBI taxonomy Id: 3562
Other names: S. oleracea, Spinacea oleracea, Spinacia oleracea L., spinach
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.