STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOVF_1032305-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (298 aa)    
Predicted Functional Partners:
SOVF_069000
Uncharacterized protein.
     
 0.940
SOVF_126920
Formyl_trans_N domain-containing protein.
    
 0.925
SOVF_055480
Uncharacterized protein.
  
  
 
0.903
SOVF_073640
Uncharacterized protein.
   
 0.823
SOVF_062630
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
  
 0.728
SOVF_148510
THF_DHG_CYH_C domain-containing protein.
    
 0.539
SOVF_117270
Uncharacterized protein.
    
 0.539
SOVF_050000
Uncharacterized protein.
     
 0.535
SOVF_205050
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.533
SOVF_082440
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.533
Your Current Organism:
Spinacia oleracea
NCBI taxonomy Id: 3562
Other names: S. oleracea, Spinacea oleracea, Spinacia oleracea L., spinach
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