STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOVF_034260AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family. (1074 aa)    
Predicted Functional Partners:
SOVF_040450
Beta-adaptin-like protein; Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
   
 0.968
SOVF_117410
Beta-adaptin-like protein; Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
   
0.965
SOVF_052910
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 0.945
SOVF_116930
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.925
SOVF_205760
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.895
SOVF_129850
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.895
SOVF_024590
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.895
SOVF_030450
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.895
SOVF_088740
Clat_adaptor_s domain-containing protein.
  
 
 0.877
SOVF_102190
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.863
Your Current Organism:
Spinacia oleracea
NCBI taxonomy Id: 3562
Other names: S. oleracea, Spinacea oleracea, Spinacia oleracea L., spinach
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