STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOVF_030630Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1061 aa)    
Predicted Functional Partners:
SOVF_135060
Uncharacterized protein.
    
 0.992
SOVF_000690
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.833
SOVF_034880
Ubiquitin-like domain-containing protein.
      
 0.703
SOVF_049760
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
      
 0.702
SOVF_040800
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
      
 0.702
SOVF_150860
Histone domain-containing protein.
    
 
 0.681
SOVF_037400
Histone H3; Belongs to the histone H3 family.
    
 
 0.681
SOVF_000590
Histone H3; Belongs to the histone H3 family.
    
 
 0.681
SOVF_003000
Uncharacterized protein.
    
 
 0.681
SOVF_000760
Histone domain-containing protein.
    
 
 0.681
Your Current Organism:
Spinacia oleracea
NCBI taxonomy Id: 3562
Other names: S. oleracea, Spinacea oleracea, Spinacia oleracea L., spinach
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.