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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa)    
Predicted Functional Partners:
SDQ46128.1
Succinate dehydrogenase / fumarate reductase flavoprotein subunit.
 
 0.994
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.989
SDQ56677.1
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 0.975
SDQ86016.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.969
SDQ45992.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.967
SDQ46154.1
Succinate dehydrogenase subunit B.
  
 0.967
SDQ46018.1
Succinate dehydrogenase subunit A.
 
 0.964
SDQ95225.1
NAD-dependent formate dehydrogenase flavoprotein subunit.
   
 0.957
SDQ47045.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.956
SDQ40634.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.947
Your Current Organism:
Thermostaphylospora chromogena
NCBI taxonomy Id: 35622
Other names: ATCC 43196, Actinobifida chromogena, DSM 43794, IFO 16096, JCM 6244, NBRC 16096, NCIB 10212, NCIB:10212, NCIMB 10212, NRRL B-16983, T. chromogena, Thermomonospora chromogena, strain Agre no. 577
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