node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDQ75494.1 | SDQ75594.1 | SAMN04489764_1992 | SAMN04489764_1996 | Glutaredoxin-like domain. | uroporphyrinogen-III synthase. | 0.689 |
SDQ75494.1 | SDQ82172.1 | SAMN04489764_1992 | SAMN04489764_2254 | Glutaredoxin-like domain. | PAS domain S-box-containing protein. | 0.661 |
SDQ75494.1 | SDR25297.1 | SAMN04489764_1992 | SAMN04489764_4484 | Glutaredoxin-like domain. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.780 |
SDQ75494.1 | SDR27833.1 | SAMN04489764_1992 | SAMN04489764_4717 | Glutaredoxin-like domain. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.955 |
SDQ75494.1 | SDR32086.1 | SAMN04489764_1992 | SAMN04489764_5128 | Glutaredoxin-like domain. | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.955 |
SDQ75494.1 | hemA | SAMN04489764_1992 | SAMN04489764_1994 | Glutaredoxin-like domain. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.650 |
SDQ75494.1 | hemC | SAMN04489764_1992 | SAMN04489764_1995 | Glutaredoxin-like domain. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.650 |
SDQ75494.1 | msrA | SAMN04489764_1992 | SAMN04489764_2030 | Glutaredoxin-like domain. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.911 |
SDQ75494.1 | rex | SAMN04489764_1992 | SAMN04489764_1993 | Glutaredoxin-like domain. | Redox-sensing transcriptional repressor; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.685 |
SDQ75494.1 | ribBA | SAMN04489764_1992 | SAMN04489764_3464 | Glutaredoxin-like domain. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.770 |
SDQ75594.1 | SDQ75494.1 | SAMN04489764_1996 | SAMN04489764_1992 | uroporphyrinogen-III synthase. | Glutaredoxin-like domain. | 0.689 |
SDQ75594.1 | SDR25297.1 | SAMN04489764_1996 | SAMN04489764_4484 | uroporphyrinogen-III synthase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.557 |
SDQ75594.1 | hemA | SAMN04489764_1996 | SAMN04489764_1994 | uroporphyrinogen-III synthase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.992 |
SDQ75594.1 | hemC | SAMN04489764_1996 | SAMN04489764_1995 | uroporphyrinogen-III synthase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
SDQ75594.1 | rex | SAMN04489764_1996 | SAMN04489764_1993 | uroporphyrinogen-III synthase. | Redox-sensing transcriptional repressor; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.831 |
SDQ75594.1 | ribBA | SAMN04489764_1996 | SAMN04489764_3464 | uroporphyrinogen-III synthase. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.540 |
SDQ82172.1 | SDQ75494.1 | SAMN04489764_2254 | SAMN04489764_1992 | PAS domain S-box-containing protein. | Glutaredoxin-like domain. | 0.661 |
SDQ82172.1 | SDR25297.1 | SAMN04489764_2254 | SAMN04489764_4484 | PAS domain S-box-containing protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.735 |
SDQ82172.1 | ribBA | SAMN04489764_2254 | SAMN04489764_3464 | PAS domain S-box-containing protein. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.884 |
SDR25297.1 | SDQ75494.1 | SAMN04489764_4484 | SAMN04489764_1992 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutaredoxin-like domain. | 0.780 |