SDQ81677.1 protein (Thermostaphylospora chromogena)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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protein homology

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Score

SDQ81677.1

Phosphotransferase enzyme family protein. (256 aa)

Predicted Functional Partners:

SDQ29570.1

0.585

SDQ81702.1

0.499

SDR23902.1

0.424

SDQ69016.1

0.419

mtnA

0.414

SDR23165.1

0.411

SDQ81656.1

0.406

SDR33698.1

0.406

Your Current Organism:

Thermostaphylospora chromogena

NCBI taxonomy Id: 35622
Other names: ATCC 43196, Actinobifida chromogena, DSM 43794, IFO 16096, JCM 6244, NBRC 16096, NCIB 10212, NCIB:10212, NCIMB 10212, NRRL B-16983, T. chromogena, Thermomonospora chromogena, strain Agre no. 577

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDQ29570.1	SDQ81677.1	SAMN04489764_0083	SAMN04489764_2235	Acyl transferase domain-containing protein.	Phosphotransferase enzyme family protein.	0.585
SDQ29570.1	SDR23165.1	SAMN04489764_0083	SAMN04489764_4286	Acyl transferase domain-containing protein.	Acyl transferase domain-containing protein.	0.999
SDQ29570.1	SDR33698.1	SAMN04489764_0083	SAMN04489764_5318	Acyl transferase domain-containing protein.	Phosphopantetheine attachment site.	0.999
SDQ29570.1	mtnA	SAMN04489764_0083	SAMN04489764_3632	Acyl transferase domain-containing protein.	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	0.436
SDQ69016.1	SDQ81677.1	SAMN04489764_1708	SAMN04489764_2235	Protein N-acetyltransferase, RimJ/RimL family.	Phosphotransferase enzyme family protein.	0.419
SDQ81656.1	SDQ81677.1	SAMN04489764_2234	SAMN04489764_2235	Pentapeptide repeat-containing protein.	Phosphotransferase enzyme family protein.	0.406
SDQ81677.1	SDQ29570.1	SAMN04489764_2235	SAMN04489764_0083	Phosphotransferase enzyme family protein.	Acyl transferase domain-containing protein.	0.585
SDQ81677.1	SDQ69016.1	SAMN04489764_2235	SAMN04489764_1708	Phosphotransferase enzyme family protein.	Protein N-acetyltransferase, RimJ/RimL family.	0.419
SDQ81677.1	SDQ81656.1	SAMN04489764_2235	SAMN04489764_2234	Phosphotransferase enzyme family protein.	Pentapeptide repeat-containing protein.	0.406
SDQ81677.1	SDQ81702.1	SAMN04489764_2235	SAMN04489764_2236	Phosphotransferase enzyme family protein.	Hypothetical protein.	0.499
SDQ81677.1	SDR23165.1	SAMN04489764_2235	SAMN04489764_4286	Phosphotransferase enzyme family protein.	Acyl transferase domain-containing protein.	0.411
SDQ81677.1	SDR23902.1	SAMN04489764_2235	SAMN04489764_4357	Phosphotransferase enzyme family protein.	Thiosulfate dehydrogenase [quinone] large subunit.	0.424
SDQ81677.1	SDR33698.1	SAMN04489764_2235	SAMN04489764_5318	Phosphotransferase enzyme family protein.	Phosphopantetheine attachment site.	0.406
SDQ81677.1	mtnA	SAMN04489764_2235	SAMN04489764_3632	Phosphotransferase enzyme family protein.	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	0.414
SDQ81702.1	SDQ81677.1	SAMN04489764_2236	SAMN04489764_2235	Hypothetical protein.	Phosphotransferase enzyme family protein.	0.499
SDR23165.1	SDQ29570.1	SAMN04489764_4286	SAMN04489764_0083	Acyl transferase domain-containing protein.	Acyl transferase domain-containing protein.	0.999
SDR23165.1	SDQ81677.1	SAMN04489764_4286	SAMN04489764_2235	Acyl transferase domain-containing protein.	Phosphotransferase enzyme family protein.	0.411
SDR23165.1	SDR33698.1	SAMN04489764_4286	SAMN04489764_5318	Acyl transferase domain-containing protein.	Phosphopantetheine attachment site.	0.992
SDR23902.1	SDQ81677.1	SAMN04489764_4357	SAMN04489764_2235	Thiosulfate dehydrogenase [quinone] large subunit.	Phosphotransferase enzyme family protein.	0.424
SDR33698.1	SDQ29570.1	SAMN04489764_5318	SAMN04489764_0083	Phosphopantetheine attachment site.	Acyl transferase domain-containing protein.	0.999

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Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.841

expected number of edges:

12

PPI enrichment p-value:

2.05e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006525

Arginine metabolic process

5 of 17

2.47

4.11

9.95e-09

GO:0006596

Polyamine biosynthetic process

4 of 6

2.83

3.92

5.41e-08

GO:0044106

Cellular amine metabolic process

5 of 28

2.26

3.62

4.43e-08

GO:0006591

Ornithine metabolic process

4 of 10

2.61

3.59

1.64e-07

GO:0009446

Putrescine biosynthetic process

3 of 4

2.88

2.91

4.64e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008783

Agmatinase activity

2 of 3

2.83

1.03

0.0136

GO:0008483

Transaminase activity

3 of 40

1.88

0.96

0.0136

GO:0030170

Pyridoxal phosphate binding

3 of 71

1.63

0.91

0.0140

GO:0003824

Catalytic activity

11 of 4543

0.39

0.3

0.0140

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:13423

Mixed, incl. Arginine metabolic process, and ArgE/DapE/ACY1/CPG2/YscS, conserved site

9 of 36

2.4

7.74

1.27e-17

CL:13427

Arginine metabolic process, and ArgE/DapE/ACY1/CPG2/YscS, conserved site

7 of 20

2.55

6.69

3.29e-14

CL:13431

Arginine metabolic process

4 of 13

2.49

3.35

3.90e-07

CL:13470

Mixed, incl. Polyamine biosynthetic process, and Saccharopine dehydrogenase activity

2 of 10

2.31

0.97

0.0160

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00330

Arginine and proline metabolism

5 of 84

1.78

2.43

1.95e-06

map00220

Arginine biosynthesis

3 of 37

1.92

1.7

0.00035

map01110

Biosynthesis of secondary metabolites

6 of 955

0.8

0.59

0.0048

map01100

Metabolic pathways

11 of 3183

0.54

0.47

7.92e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-351202

Metabolism of polyamines

4 of 14

2.46

3.2

7.28e-07

MAP-351143

Agmatine biosynthesis

3 of 4

2.88

2.79

7.78e-06

MAP-71291

Metabolism of amino acids and derivatives

8 of 353

1.36

1.93

1.57e-07

MAP-8964539

Glutamate and glutamine metabolism

2 of 18

2.05

0.77

0.0369

MAP-1430728

Metabolism

8 of 2109

0.59

0.36

0.0369

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00202

Aminotransferase class-III

3 of 7

2.64

2.2

8.79e-05

PF00491

Arginase family

2 of 4

2.71

1.19

0.0068

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005814

Aminotransferase class-III

3 of 7

2.64

1.96

0.00025

IPR020855

Ureohydrolase, manganese-binding site

2 of 4

2.71

0.95

0.0192

IPR006035

Ureohydrolase

2 of 4

2.71

0.95

0.0192

IPR023696

Ureohydrolase domain superfamily

2 of 8

2.4

0.94

0.0192

IPR015424

Pyridoxal phosphate-dependent transferase

3 of 52

1.77

0.87

0.0192

(more ...)

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