SDW70961.1 protein (Albimonas donghaensis) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:

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Score

SDW70961.1

Cysteine-rich secretory protein family protein. (425 aa)

Predicted Functional Partners:

SDW12769.1

0.782

SDX13772.1

0.781

SDX32259.1

0.780

SDW82983.1

0.764

SDW18167.1

0.747

SDW10227.1

0.667

SDX85775.1

0.661

SDX05248.1

0.649

SDX06546.1

0.643

SDW46505.1

0.638

Your Current Organism:

Albimonas donghaensis

NCBI taxonomy Id: 356660
Other names: A. donghaensis, Albimonas donghaensis Lim et al. 2008, DSM 17890, KCTC 12586, Paracoccus sp. DS2, strain DS2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDW10227.1	SDW12769.1	SAMN05444336_101140	SAMN05444336_101196	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.575
SDW10227.1	SDW18167.1	SAMN05444336_101140	SAMN05444336_101343	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.714
SDW10227.1	SDW70961.1	SAMN05444336_101140	SAMN05444336_102153	Hemolysin-type calcium-binding repeat-containing protein.	Cysteine-rich secretory protein family protein.	0.667
SDW10227.1	SDW82983.1	SAMN05444336_101140	SAMN05444336_102465	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.590
SDW10227.1	SDX06546.1	SAMN05444336_101140	SAMN05444336_103189	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.441
SDW10227.1	SDX32259.1	SAMN05444336_101140	SAMN05444336_104294	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.707
SDW12769.1	SDW10227.1	SAMN05444336_101196	SAMN05444336_101140	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.575
SDW12769.1	SDW18167.1	SAMN05444336_101196	SAMN05444336_101343	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.519
SDW12769.1	SDW70961.1	SAMN05444336_101196	SAMN05444336_102153	Hemolysin-type calcium-binding repeat-containing protein.	Cysteine-rich secretory protein family protein.	0.782
SDW12769.1	SDW82983.1	SAMN05444336_101196	SAMN05444336_102465	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.528
SDW12769.1	SDX06546.1	SAMN05444336_101196	SAMN05444336_103189	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.558
SDW12769.1	SDX13772.1	SAMN05444336_101196	SAMN05444336_103410	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.561
SDW12769.1	SDX32259.1	SAMN05444336_101196	SAMN05444336_104294	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.525
SDW18167.1	SDW10227.1	SAMN05444336_101343	SAMN05444336_101140	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.714
SDW18167.1	SDW12769.1	SAMN05444336_101343	SAMN05444336_101196	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.519
SDW18167.1	SDW70961.1	SAMN05444336_101343	SAMN05444336_102153	Hemolysin-type calcium-binding repeat-containing protein.	Cysteine-rich secretory protein family protein.	0.747
SDW18167.1	SDX06546.1	SAMN05444336_101343	SAMN05444336_103189	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.584
SDW18167.1	SDX13772.1	SAMN05444336_101343	SAMN05444336_103410	Hemolysin-type calcium-binding repeat-containing protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.581
SDW46505.1	SDW70961.1	SAMN05444336_1011090	SAMN05444336_102153	Hypothetical protein.	Cysteine-rich secretory protein family protein.	0.638
SDW70961.1	SDW10227.1	SAMN05444336_102153	SAMN05444336_101140	Cysteine-rich secretory protein family protein.	Hemolysin-type calcium-binding repeat-containing protein.	0.667

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

23

average node degree:

4.18

avg. local clustering coefficient:

0.766

expected number of edges:

10

PPI enrichment p-value:

0.000392

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008658

Penicillin binding

4 of 4

2.28

2.48

1.55e-05

GO:0009002

Serine-type D-Ala-D-Ala carboxypeptidase activity

3 of 3

2.28

2.0

0.00015

GO:0008236

Serine-type peptidase activity

4 of 16

1.68

1.69

0.00015

GO:0008955

Peptidoglycan glycosyltransferase activity

2 of 2

2.28

1.2

0.0059

GO:0008745

N-acetylmuramoyl-L-alanine amidase activity

2 of 4

1.98

0.98

0.0136

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:961

Penicillin binding, and Cell cycle protein

5 of 7

2.13

3.25

1.64e-07

CL:938

Cell division, and Regulation of cell shape

8 of 56

1.43

2.19

3.37e-08

CL:1011

Response to bacterium, and Peptidase M50

3 of 6

1.98

1.62

0.00059

CL:1472

Two-component regulatory system

2 of 6

1.8

0.77

0.0320

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00550

Peptidoglycan biosynthesis

6 of 28

1.61

2.33

5.28e-07

map01503

Cationic antimicrobial peptide (CAMP) resistance

3 of 19

1.48

0.94

0.0084

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005576

Extracellular region

4 of 52

1.17

0.66

0.0248

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00905

Penicillin binding protein transpeptidase domain

4 of 4

2.28

2.58

9.41e-06

PF03717

Penicillin-binding Protein dimerisation domain

2 of 2

2.28

0.87

0.0249

PF00912

Transglycosylase

2 of 2

2.28

0.87

0.0249

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR012338

Beta-lactamase/transpeptidase-like

5 of 7

2.13

2.92

1.03e-06

IPR001460

Penicillin-binding protein, transpeptidase

4 of 4

2.28

2.5

1.37e-05

IPR036950

Penicillin binding protein transglycosylase domain

2 of 2

2.28

0.72

0.0483

IPR036138

Penicillin-binding protein, dimerisation domain superfamily

2 of 2

2.28

0.72

0.0483

IPR005543

PASTA domain

2 of 2

2.28

0.72

0.0483

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00740

PASTA

2 of 2

2.28

1.02

0.0127

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