STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VMCG_00381Uncharacterized protein. (416 aa)    
Predicted Functional Partners:
VMCG_08142
DNA helicase; Belongs to the MCM family.
   
  
 0.926
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
  
 0.905
VMCG_02346
DNA helicase; Belongs to the MCM family.
   
  
 0.898
VMCG_00900
DNA helicase; Belongs to the MCM family.
   
  
 0.898
VMCG_02205
DNA helicase; Belongs to the MCM family.
   
    0.895
VMCG_05647
Nucleoside diphosphate kinase.
    
 0.848
VMCG_03671
Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.837
VMCG_05607
Thymidylate_kin domain-containing protein.
   
 
 0.831
ADK1
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
     
 0.825
VMCG_04126
Guanylate kinase-like domain-containing protein.
   
 
 0.819
Your Current Organism:
Valsa malicola
NCBI taxonomy Id: 356882
Other names: V. malicola
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