node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMG52243.1 | psd | AL524_03565 | AL524_05820 | Phospholipase; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.919 |
AMG52243.1 | pssA | AL524_03565 | AL524_08880 | Phospholipase; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | Catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
AMG52998.1 | AMG54025.1 | AL524_07810 | AL524_13525 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.903 |
AMG52998.1 | glyA | AL524_07810 | AL524_09390 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.944 |
AMG52998.1 | ilvA | AL524_07810 | AL524_03315 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.913 |
AMG52998.1 | pssA | AL524_07810 | AL524_08880 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
AMG52998.1 | serB | AL524_07810 | AL524_06935 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphoserine phosphatase; Catalyzes the formation of serine from O-phosphoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
AMG54025.1 | AMG52998.1 | AL524_13525 | AL524_07810 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.903 |
AMG54025.1 | glyA | AL524_13525 | AL524_09390 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.944 |
AMG54025.1 | ilvA | AL524_13525 | AL524_03315 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.913 |
AMG54025.1 | pssA | AL524_13525 | AL524_08880 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
AMG54025.1 | serB | AL524_13525 | AL524_06935 | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphoserine phosphatase; Catalyzes the formation of serine from O-phosphoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
cdh | cdsA | AL524_04300 | AL524_21590 | CDP-diacylglycerol pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. | 0.900 |
cdh | pgsA | AL524_04300 | AL524_12965 | CDP-diacylglycerol pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
cdh | pssA | AL524_04300 | AL524_08880 | CDP-diacylglycerol pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.914 |
cdsA | cdh | AL524_21590 | AL524_04300 | Catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. | CDP-diacylglycerol pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
cdsA | pgsA | AL524_21590 | AL524_12965 | Catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.952 |
cdsA | psd | AL524_21590 | AL524_05820 | Catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.417 |
cdsA | pssA | AL524_21590 | AL524_08880 | Catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. | Catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
glyA | AMG52998.1 | AL524_09390 | AL524_07810 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine dehydratase; Catalyzes the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.944 |