STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaAtRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)    
Predicted Functional Partners:
rcsF
Colanic acid biosynthesis protein RcsF; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
      0.942
cobB
NAD-dependent deacylase; Modulates the activities of several enzymes which are inactive in their acetylated form; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
      
 0.644
metQ
DL-methionine transporter substrate-binding subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nlpA lipoprotein family.
      0.638
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
       0.566
metN
DL-methionine transporter ATP-binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
       0.484
tmcA
tRNA cytosine(34) acetyltransferase TmcA; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
   
 0.467
AMG55440.1
DL-methionine transporter permease subunit; Part of the MetNIQ methionine uptake system; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.442
AMG56051.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.414
AMG55445.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.411
Your Current Organism:
Citrobacter amalonaticus
NCBI taxonomy Id: 35703
Other names: ATCC 25405, C. amalonaticus, CCUG 4860, CECT 863, CIP 82.89, Citrobacter intermedius biogroup a, DSM 4593, LMG 7873, LMG:7873, Levinea amalonatica, NCTC 10805
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