STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sgrRTranscriptional regulator SgrR; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain. (551 aa)    
Predicted Functional Partners:
AMG52378.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.678
LeuD
3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.678
leuD
Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
      
 0.678
mutH
DNA mismatch repair protein MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.
      
 0.623
AMG55564.1
Inhibitor of glucose transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.592
AMG53310.1
Enhanced serine sensitivity protein SseB; Enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.555
thiP
Permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.543
frsA
Fermentation/respiration switch protein; Forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0255 family.
  
     0.529
tbpA
Thiamine ABC transporter substrate-binding protein; Part of the thiamine and TPP transport system tbpA-thiPQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.528
wecH
Acetyltransferase; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
     0.509
Your Current Organism:
Citrobacter amalonaticus
NCBI taxonomy Id: 35703
Other names: ATCC 25405, C. amalonaticus, CCUG 4860, CECT 863, CIP 82.89, Citrobacter intermedius biogroup a, DSM 4593, LMG 7873, LMG:7873, Levinea amalonatica, NCTC 10805
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