node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ftsY | lepB | OTBS_0336 | OTBS_1702 | Tetratricopeptide repeat protein with 1 trp repeats. | Transposase and inactivated derivative; Belongs to the peptidase S26 family. | 0.827 |
ftsY | secB | OTBS_0336 | OTBS_2155 | Tetratricopeptide repeat protein with 1 trp repeats. | Transposase and inactivated derivative; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.976 |
ftsY | secD | OTBS_0336 | OTBS_1761 | Tetratricopeptide repeat protein with 1 trp repeats. | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.784 |
ftsY | secF | OTBS_0336 | OTBS_1033 | Tetratricopeptide repeat protein with 1 trp repeats. | Transposase and inactivated derivative; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.573 |
ftsY | secY | OTBS_0336 | OTBS_0357 | Tetratricopeptide repeat protein with 1 trp repeats. | Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.994 |
ftsY | serS | OTBS_0336 | OTBS_1037 | Tetratricopeptide repeat protein with 1 trp repeats. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.567 |
ftsY | tatA | OTBS_0336 | OTBS_0925 | Tetratricopeptide repeat protein with 1 trp repeats. | Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.789 |
ftsY | tatC | OTBS_0336 | OTBS_1038 | Tetratricopeptide repeat protein with 1 trp repeats. | Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.783 |
ftsY | yajC | OTBS_0336 | OTBS_1760 | Tetratricopeptide repeat protein with 1 trp repeats. | Transposase and inactivated derivative; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.977 |
ftsY | yidC | OTBS_0336 | OTBS_1416 | Tetratricopeptide repeat protein with 1 trp repeats. | 60 kD inner-membrane protein, preprotein translocase subunit; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.980 |
lepB | ftsY | OTBS_1702 | OTBS_0336 | Transposase and inactivated derivative; Belongs to the peptidase S26 family. | Tetratricopeptide repeat protein with 1 trp repeats. | 0.827 |
lepB | secD | OTBS_1702 | OTBS_1761 | Transposase and inactivated derivative; Belongs to the peptidase S26 family. | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.852 |
lepB | secF | OTBS_1702 | OTBS_1033 | Transposase and inactivated derivative; Belongs to the peptidase S26 family. | Transposase and inactivated derivative; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.740 |
lepB | secY | OTBS_1702 | OTBS_0357 | Transposase and inactivated derivative; Belongs to the peptidase S26 family. | Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.824 |
lepB | tatA | OTBS_1702 | OTBS_0925 | Transposase and inactivated derivative; Belongs to the peptidase S26 family. | Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.786 |
lepB | tatC | OTBS_1702 | OTBS_1038 | Transposase and inactivated derivative; Belongs to the peptidase S26 family. | Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.816 |
lepB | yajC | OTBS_1702 | OTBS_1760 | Transposase and inactivated derivative; Belongs to the peptidase S26 family. | Transposase and inactivated derivative; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.843 |
lepB | yidC | OTBS_1702 | OTBS_1416 | Transposase and inactivated derivative; Belongs to the peptidase S26 family. | 60 kD inner-membrane protein, preprotein translocase subunit; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.837 |
secB | ftsY | OTBS_2155 | OTBS_0336 | Transposase and inactivated derivative; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | Tetratricopeptide repeat protein with 1 trp repeats. | 0.976 |
secB | secD | OTBS_2155 | OTBS_1761 | Transposase and inactivated derivative; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.779 |