STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grlAGlutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. (124 aa)    
Predicted Functional Partners:
bolA
BolA-like putative stress-induced morphogen; Belongs to the BolA/IbaG family.
  
 
 0.999
OTBS_1710
Conserved hypothetical protein.
  
 
 0.868
iscA
Iron-binding protein IscA/HesB; Belongs to the HesB/IscA family.
  
 0.861
iscA-2
Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
  
 0.861
hscB
Co-chaperone protein; Belongs to the HscB family.
    
 0.828
grxC
Conjugative transfer protein.
 
 
 0.749
tdpX1
Thioredoxin peroxidase 1.
  
 
 0.693
iscU
FeS cluster assembly scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.644
map
Transposase and inactivated derivative; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
 
  
 0.618
lpdA
Dihydrolipoamide dehydrogenase.
  
  
 0.616
Your Current Organism:
Orientia tsutsugamushi
NCBI taxonomy Id: 357244
Other names: O. tsutsugamushi str. Boryong, Orientia tsutsugamushi Boryong, Orientia tsutsugamushi str. Boryong, Orientia tsutsugamushi strain Boryong
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.