STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hflCPutative membrane protease, stomatin/prohibitin-like protein. (316 aa)    
Predicted Functional Partners:
ftsH
ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.963
htpG
Heat shock protein; Molecular chaperone. Has ATPase activity.
  
 
 0.659
gltP
Putative proton/glutamate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
   
 0.652
tig
Transposase and inactivated derivative.
   
  
 0.577
hflK
Putative membrane bound protease protein; HflC and HflK could encode or regulate a protease.
      
 0.570
cycC
Conjugative transfer protein.
  
  
 0.517
dnaK
Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.503
yidC
60 kD inner-membrane protein, preprotein translocase subunit; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
 
 0.471
tnA-15
Transposase and inactivated derivative.
  
 
 0.467
coxB
Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
 
 0.462
Your Current Organism:
Orientia tsutsugamushi
NCBI taxonomy Id: 357244
Other names: O. tsutsugamushi str. Boryong, Orientia tsutsugamushi Boryong, Orientia tsutsugamushi str. Boryong, Orientia tsutsugamushi strain Boryong
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.