STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRO06982.1Catabolite control protein A. (333 aa)    
Predicted Functional Partners:
KRO05703.1
Phosphocarrier protein HPr.
   
 
 0.913
KRO06983.1
Proline dipeptidase.
  
 
 0.840
hprK
HPr kinase phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...]
      
 0.769
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
    
 
 0.707
KRO06655.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 
 0.650
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 
 0.625
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
   
 
 0.607
KRO05826.1
Bifunctional acetaldehyde-CoA alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 
 0.567
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
   0.565
hrcA
Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
      
 0.565
Your Current Organism:
Lactobacillus parabrevis
NCBI taxonomy Id: 357278
Other names: ATCC 53295, L. parabrevis, LMG 11984, LMG:11984, Lactobacillus parabrevis Vancanneyt et al. 2006
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