node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRO04998.1 | KRO05412.1 | IV61_GL001771 | IV61_GL001347 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase. | 0.958 |
KRO04998.1 | KRO05752.1 | IV61_GL001771 | IV61_GL000974 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.956 |
KRO04998.1 | KRO06228.1 | IV61_GL001771 | IV61_GL000376 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase. | 0.955 |
KRO04998.1 | apt | IV61_GL001771 | IV61_GL001750 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.973 |
KRO04998.1 | gmk | IV61_GL001771 | IV61_GL000264 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.955 |
KRO04998.1 | guaA | IV61_GL001771 | IV61_GL000398 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.984 |
KRO04998.1 | guaC | IV61_GL001771 | IV61_GL001705 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanosine 5-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.957 |
KRO04998.1 | purA | IV61_GL001771 | IV61_GL001706 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.976 |
KRO04998.1 | purH | IV61_GL001771 | IV61_GL002301 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Bifunctional purine biosynthesis protein purh. | 0.964 |
KRO04998.1 | xpt | IV61_GL001771 | IV61_GL000862 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.963 |
KRO05412.1 | KRO04998.1 | IV61_GL001347 | IV61_GL001771 | Adenine phosphoribosyltransferase. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.958 |
KRO05412.1 | KRO06228.1 | IV61_GL001347 | IV61_GL000376 | Adenine phosphoribosyltransferase. | Guanylate kinase. | 0.964 |
KRO05412.1 | gmk | IV61_GL001347 | IV61_GL000264 | Adenine phosphoribosyltransferase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.964 |
KRO05412.1 | guaA | IV61_GL001347 | IV61_GL000398 | Adenine phosphoribosyltransferase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.985 |
KRO05412.1 | guaC | IV61_GL001347 | IV61_GL001705 | Adenine phosphoribosyltransferase. | Guanosine 5-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.957 |
KRO05412.1 | purA | IV61_GL001347 | IV61_GL001706 | Adenine phosphoribosyltransferase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.707 |
KRO05412.1 | purH | IV61_GL001347 | IV61_GL002301 | Adenine phosphoribosyltransferase. | Bifunctional purine biosynthesis protein purh. | 0.971 |
KRO05412.1 | xpt | IV61_GL001347 | IV61_GL000862 | Adenine phosphoribosyltransferase. | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.952 |
KRO05752.1 | KRO04998.1 | IV61_GL000974 | IV61_GL001771 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.956 |
KRO05752.1 | apt | IV61_GL000974 | IV61_GL001750 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.420 |