STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (268 aa)    
Predicted Functional Partners:
SFR34996.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.960
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.926
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.909
SFR37252.1
Branched-chain amino acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.909
SFR44153.1
Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase.
 
   
 0.659
SFR30518.1
Hypothetical protein.
       0.586
SFR51917.1
BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase.
  
  
 0.584
SFR34729.1
PGF-CTERM protein/surface glycoprotein.
      
 0.509
SFR36524.1
CARDB protein.
      
 0.509
SFR45079.1
Cytochrome c oxidase subunit I+III; Belongs to the heme-copper respiratory oxidase family.
       0.497
Your Current Organism:
Halorubrum sodomense
NCBI taxonomy Id: 35743
Other names: ATCC 33755, CIP 105330, DSM 3755, H. sodomense, Halobacterium sodomense, Halobacterium sodomitanum, Halobacterium sodomiticum, Halorubrobacterium sodomense, IFO 14740, JCM 8880, NBRC 14740, NCIMB 2197, strain RD-26
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