STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl40eLarge subunit ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa)    
Predicted Functional Partners:
rpl1
Large subunit ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
  
 0.999
rpl2
Large subunit ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 0.999
rps19p
Small subunit ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 0.999
rps3
Small subunit ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 0.999
rpl29
Large subunit ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
  
 0.999
rps17
Small subunit ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 0.999
rpl14
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 0.999
rps4e
Small subunit ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.
   
 0.999
rpl5
Large subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
   
 0.999
rps14
Small subunit ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
   
 0.999
Your Current Organism:
Halorubrum sodomense
NCBI taxonomy Id: 35743
Other names: ATCC 33755, CIP 105330, DSM 3755, H. sodomense, Halobacterium sodomense, Halobacterium sodomitanum, Halobacterium sodomiticum, Halorubrobacterium sodomense, IFO 14740, JCM 8880, NBRC 14740, NCIMB 2197, strain RD-26
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