STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR44096.1methylmalonyl-CoA mutase, N-terminal domain. (566 aa)    
Predicted Functional Partners:
SFR36147.1
methylmalonyl-CoA mutase, C-terminal domain.
 0.999
SFR36159.1
LAO/AO transport system kinase.
  
 0.981
SFR48468.1
methylmalonyl-CoA epimerase.
 
  
 0.971
SFR32942.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 
 0.953
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.907
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.903
SFR39234.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
     
 0.893
SFR39244.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.893
SFR48481.1
methylmalonyl-CoA mutase, N-terminal domain.
  
  
 
0.890
SFR30270.1
Malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily.
     
 0.855
Your Current Organism:
Halorubrum sodomense
NCBI taxonomy Id: 35743
Other names: ATCC 33755, CIP 105330, DSM 3755, H. sodomense, Halobacterium sodomense, Halobacterium sodomitanum, Halobacterium sodomiticum, Halorubrobacterium sodomense, IFO 14740, JCM 8880, NBRC 14740, NCIMB 2197, strain RD-26
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.