node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFR30422.1 | SFR32656.1 | SAMN04487937_0243 | SAMN04487937_1100 | Replicative DNA helicase Mcm. | Replication factor A1. | 0.852 |
SFR30422.1 | SFR60766.1 | SAMN04487937_0243 | SAMN04487937_3060 | Replicative DNA helicase Mcm. | Cell division control protein 6; Involved in regulation of DNA replication. | 0.824 |
SFR30422.1 | pcn | SAMN04487937_0243 | SAMN04487937_0091 | Replicative DNA helicase Mcm. | Proliferating cell antigen; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.944 |
SFR30422.1 | polC | SAMN04487937_0243 | SAMN04487937_1146 | Replicative DNA helicase Mcm. | DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. | 0.607 |
SFR30422.1 | priL | SAMN04487937_0243 | SAMN04487937_0276 | Replicative DNA helicase Mcm. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.988 |
SFR30422.1 | priS | SAMN04487937_0243 | SAMN04487937_0483 | Replicative DNA helicase Mcm. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.972 |
SFR30716.1 | SFR34884.1 | SAMN04487937_0544 | SAMN04487937_1370 | Putative nucleotide binding protein. | Hypothetical protein; Involved in DNA damage repair. | 0.642 |
SFR30716.1 | SFR60766.1 | SAMN04487937_0544 | SAMN04487937_3060 | Putative nucleotide binding protein. | Cell division control protein 6; Involved in regulation of DNA replication. | 0.623 |
SFR30716.1 | dnaG | SAMN04487937_0544 | SAMN04487937_0492 | Putative nucleotide binding protein. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.698 |
SFR30716.1 | polC | SAMN04487937_0544 | SAMN04487937_1146 | Putative nucleotide binding protein. | DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. | 0.602 |
SFR32656.1 | SFR30422.1 | SAMN04487937_1100 | SAMN04487937_0243 | Replication factor A1. | Replicative DNA helicase Mcm. | 0.852 |
SFR32656.1 | SFR38765.1 | SAMN04487937_1100 | SAMN04487937_1761 | Replication factor A1. | Phosphate uptake regulator. | 0.612 |
SFR32656.1 | SFR60766.1 | SAMN04487937_1100 | SAMN04487937_3060 | Replication factor A1. | Cell division control protein 6; Involved in regulation of DNA replication. | 0.557 |
SFR32656.1 | pcn | SAMN04487937_1100 | SAMN04487937_0091 | Replication factor A1. | Proliferating cell antigen; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.753 |
SFR32656.1 | priL | SAMN04487937_1100 | SAMN04487937_0276 | Replication factor A1. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.592 |
SFR32656.1 | priS | SAMN04487937_1100 | SAMN04487937_0483 | Replication factor A1. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.494 |
SFR34884.1 | SFR30716.1 | SAMN04487937_1370 | SAMN04487937_0544 | Hypothetical protein; Involved in DNA damage repair. | Putative nucleotide binding protein. | 0.642 |
SFR34884.1 | SFR38765.1 | SAMN04487937_1370 | SAMN04487937_1761 | Hypothetical protein; Involved in DNA damage repair. | Phosphate uptake regulator. | 0.523 |
SFR34884.1 | SFR60766.1 | SAMN04487937_1370 | SAMN04487937_3060 | Hypothetical protein; Involved in DNA damage repair. | Cell division control protein 6; Involved in regulation of DNA replication. | 0.609 |
SFR34884.1 | dnaG | SAMN04487937_1370 | SAMN04487937_0492 | Hypothetical protein; Involved in DNA damage repair. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.612 |