STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFE52003.1Membrane protein implicated in regulation of membrane protease activity. (146 aa)    
Predicted Functional Partners:
SFE51980.1
Regulator of protease activity HflC, stomatin/prohibitin superfamily.
 
  
 0.979
SFE38194.1
Flotillin.
  
  
 0.880
SFF05696.1
Precorrin-2 C20-methyltransferase / precorrin-3B C17-methyltransferase.
  
    0.861
cobS
adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
   
    0.858
SFE38979.1
Regulator of protease activity HflC, stomatin/prohibitin superfamily.
 
  
 0.695
SFE52039.1
CubicO group peptidase, beta-lactamase class C family.
  
    0.652
SFE52149.1
Hypothetical protein.
     
 0.593
SFF14216.1
Uncharacterized membrane protein YccF, DUF307 family.
   
    0.582
SFF55254.1
Precorrin-4/cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
   
  
 0.534
cobQ
Adenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
   
    0.476
Your Current Organism:
Actinoplanes philippinensis
NCBI taxonomy Id: 35752
Other names: A. philippinensis, ATCC 12427, DSM 43019, IFO 13878, JCM 3001, NBRC 13878, NRRL 2506, VKM Ac-842
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